You get to call up to two witnesses, and can ask either for an alibi or character testimony. Positive character testimony will earn you an extra favor at the end of the defense, so the best you can hope to do is establish an alibi and then get positive character testimony.|
Venus Velva and Valencia St. Mission cost a favor each to call, but are the most reliable witnesses. Some of the other witnesses can actually incriminate you. Dagger Stilleto and Beep Boop will never help your case.
Sometimes witnesses won't pick up when you call. Spinach Arugala, Triskelion Motif, the Hive, and Beep Boop will always pick up.
Is praying worth it? Miracles happen, but not very often, and they don't always give you what you want.